guanosine 5'-diphosphate (RRSR form)
Also known as GDP, guanosine diphosphate, [[(2S,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxyphosphonic acid, [[(2S,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxyphosphonic acid, Guanosine 5'-(trihydrogen pyrophosphate), 5'-GDP, PpG, Guanosine-5'-diphosphate
Chemical data
- Formula
- C10H15N5O11P2
- Molecular weight
- 443.2 g/mol
- IUPAC name
- [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate
- SMILES
- C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N
- InChIKey
- QGWNDRXFNXRZMB-UUOKFMHZSA-N
- XLogP
- -4.6
- Polar surface area
- 248 Ų
- H-bond donors
- 7
- H-bond acceptors
- 13
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
~3 min read
Article
Guanosine diphosphate, abbreviated GDP, is a nucleoside diphosphate. It is an ester of pyrophosphoric acid with the nucleoside guanosine. GDP consists of a pyrophosphate group, a pentose sugar ribose, and the nucleobase guanine.
GDP is the product of GTP dephosphorylation by GTPases, e.g., the G-proteins that are involved in signal transduction.