diquafosol

Also known as INS-365, INS365, P1,P4-Bis(5'-uridyl) tetrahydrogen tetraphosphate, UppppU

Diquafosol (tradename Diquas) is a pharmaceutical drug for the treatment of dry eye disease. It was approved for use in Japan in 2010. It is formulated as a 3% ophthalmic solution of the tetrasodium salt.

In the Vinony graph

Within Vinony's link graph, diquafosol is referenced by 191 other articles, and connects out to adenosine receptor, copper and sodium.

It is catalogued under topics including Chembox image size set, Chemical articles with multiple CAS registry numbers and Chemical articles with multiple compound IDs.

Its subject is documented across 7 Wikipedia language editions.

Wikidata facts

Mass: 789.994

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World Health Organisation international non-proprietary name: diquafosol
chemical formula: C₁₈H₂₆N₄O₂₃P₄
isomeric SMILES: C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=CC(=O)NC4=O)O)O)O)O
canonical SMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=CC(=O)NC4=O)O)O)O)O

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Encyclopedic overview

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References

{{Chembox | ImageFile = Diquafosol.svg | ImageClass = skin-invert-image | ImageSize = 250px | IUPACName = O1,O7-Di(5′-deoxyuridin-5′-yl) tetrahydrogen tetraphosphate | SystematicName = O1,O7-Bis{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl} tetrahydrogen tetraphosphate | OtherNames = P1,P4-Bis(5'-uridyl) tetraphosphate; INS-365; Diquafosol tetrasodium |Section1= |Section2= |Section3= |Section5= | Section6 = }}

Excerpted from Wikipedia’s “diquafosol” article, available under the CC BY-SA 4.0 licence.