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deoxycytidine

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EntityQ422504· pop 26· linked from 106 articles

deoxycytidine

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Also known as 2'-Deoxycytidine, Deoxyribose cytidine, dCYD, dC, 1-(2-deoxy-.beta.-d-ribofuranosyl)cytosine, 4-amino-1-(2-deoxy-.beta.-d-erythro-pentofuranosyl)-2(1h)-pyrimidinone

Deoxycytidine is a deoxyribonucleoside, a component of deoxyribonucleic acid. It is similar to the ribonucleoside cytidine, but with one hydroxyl group removed from the C2' position. Deoxycytidine can be phosphorylated at C5' of the deoxyribose by deoxycytidine kinase, converting it to deoxycytidine monophosphate (dCMP), a DNA precursor. dCMP can be converted to dUMP and dTMP.

Chemical data

Formula
C9H13N3O4
Molecular weight
227.22 g/mol
IUPAC name
4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
SMILES
C1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)CO)O
InChIKey
CKTSBUTUHBMZGZ-SHYZEUOFSA-N
XLogP
-1.8
Polar surface area
108 Ų
H-bond donors
3
H-bond acceptors
4
Formal charge
0

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Research

39,682 papers

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Wikidata facts

Has part
oxygen
Mass
227.090605896
Show 6 more facts
found in taxon
Escherichia coli
chemical formula
C₉H₁₃N₃O₄
isomeric SMILES
c1cn(c(=O)nc1N)[C@H]2C[C@@H]([C@H](O2)CO)O
canonical SMILES
N=C1N=C(O)N(C=C1)C2OC(CO)C(O)C2
Commons category
Deoxycytidine
subject has role
primary metabolite
Sources (4)

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Encyclopedic overview

3 sections
Contents
  • Clinical significance
  • References
  • External links

Deoxycytidine is a deoxyribonucleoside, a component of deoxyribonucleic acid. It is similar to the ribonucleoside cytidine, but with one hydroxyl group removed from the C2' position. Deoxycytidine can be phosphorylated at C5' of the deoxyribose by deoxycytidine kinase, converting it to deoxycytidine monophosphate (dCMP), a DNA precursor. dCMP can be converted to dUMP and dTMP.

Doxecitine is the international nonproprietary name.

Excerpted from Wikipedia’s “deoxycytidine” article, available under the CC BY-SA 4.0 licence.