deoxycytidine
Also known as 2'-Deoxycytidine, Deoxyribose cytidine, dCYD, dC, 1-(2-deoxy-.beta.-d-ribofuranosyl)cytosine, 4-amino-1-(2-deoxy-.beta.-d-erythro-pentofuranosyl)-2(1h)-pyrimidinone
Deoxycytidine is a deoxyribonucleoside, a component of deoxyribonucleic acid. It is similar to the ribonucleoside cytidine, but with one hydroxyl group removed from the C2' position. Deoxycytidine can be phosphorylated at C5' of the deoxyribose by deoxycytidine kinase, converting it to deoxycytidine monophosphate (dCMP), a DNA precursor. dCMP can be converted to dUMP and dTMP.
Chemical data
- Formula
- C9H13N3O4
- Molecular weight
- 227.22 g/mol
- IUPAC name
- 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
- SMILES
- C1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)CO)O
- InChIKey
- CKTSBUTUHBMZGZ-SHYZEUOFSA-N
- XLogP
- -1.8
- Polar surface area
- 108 Ų
- H-bond donors
- 3
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
39,682 papersArticle
3 sectionsContents
- Clinical significance
- References
- External links
Deoxycytidine is a deoxyribonucleoside, a component of deoxyribonucleic acid. It is similar to the ribonucleoside cytidine, but with one hydroxyl group removed from the C2' position. Deoxycytidine can be phosphorylated at C5' of the deoxyribose by deoxycytidine kinase, converting it to deoxycytidine monophosphate (dCMP), a DNA precursor. dCMP can be converted to dUMP and dTMP.
Doxecitine is the international nonproprietary name.