amelogenesis
Sign in to saveAlso known as GO:0097186, enamel development
thumb | right Amelogenesis is the process of forming tooth enamel, the hard, protective outer layer of teeth. This process begins during tooth development after the initial formation of dentin (dentinogenesis), the layer beneath the enamel. The inner enamel epithelium (IEE), a layer of cells within the developing tooth, plays a crucial role by signaling the differentiation of specialized cells called ameloblasts, which then secrete the proteins and minerals that make up enamel. The formation of dentin is essential for amelogenesis to occur, and a reciprocal signaling process between the develo
Research
3,009 papers- Ameloblastin and its multifunctionality in amelogenesis: A review.Matrix biology : journal of the International Society for Matrix Biology · 2024
- Challenges of Studying Amelogenesis in Gene-Targeted Mouse Models.International journal of molecular sciences · 2025
- Developmental Defects of Enamel.Monographs in oral science · 2024
- Role of glucose metabolism in amelogenesis.Journal of oral biosciences · 2025
- Ion Transport by Ameloblasts during Amelogenesis.Journal of dental research · 2017
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Article
6 sectionsContents
- Stages
- Inductive (or pre-secretory) stage
- Secretory stage
- Maturation stage
- See also
- References
thumb | right Amelogenesis is the process of forming tooth enamel, the hard, protective outer layer of teeth. This process begins during tooth development after the initial formation of dentin (dentinogenesis), the layer beneath the enamel. The inner enamel epithelium (IEE), a layer of cells within the developing tooth, plays a crucial role by signaling the differentiation of specialized cells called ameloblasts, which then secrete the proteins and minerals that make up enamel. The formation of dentin is essential for amelogenesis to occur, and a reciprocal signaling process between the developing dentin and the IEE-derived ameloblasts ensures the proper coordination of these two crucial stages of tooth development.
==Stages==