TUFT1
Sign in to saveAlso known as entrez:7286, tuftelin 1
Tuftelin is an acidic phosphorylated glycoprotein found in tooth enamel. In humans, the tuftelin protein is encoded by the TUFT1 gene. It is an acidic protein that is thought to play a role in dental enamel mineralization and is implicated in caries susceptibility. It is also thought to be involved with adaptation to hypoxia, mesenchymal stem cell function, and neurotrophin nerve growth factor mediated neuronal differentiation.
Gene data
TUFT1- Name
- tuftelin 1
- Type
- protein-coding
- Aliases
- WHSF
Tuftelin is an acidic protein that is thought to play a role in dental enamel mineralization and is implicated in caries susceptibility. It is also thought to be involved with adaptation to hypoxia, mesenchymal stem cell function, and neurotrophin nerve growth factor mediated neuronal differentiation. [provided by RefSeq, Aug 2014].
via MyGene.info
Gene · Ensembl
tuftelin 1
- Symbol
- TUFT1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:151,540,305-151,583,583
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 7985
- exact match
- identifiers.org/ncbigene/7286
- genomic start
- 151512781
- genomic end
- 151556059
- cytogenetic location
- 1q21.3
Sources (3)
via Wikidata · CC0
~1 min read
Article
6 sectionsContents
- Classification
- Function
- Research
- Interactions
- References
- Further reading
Tuftelin is an acidic phosphorylated glycoprotein found in tooth enamel. In humans, the tuftelin protein is encoded by the TUFT1 gene. It is an acidic protein that is thought to play a role in dental enamel mineralization and is implicated in caries susceptibility. It is also thought to be involved with adaptation to hypoxia, mesenchymal stem cell function, and neurotrophin nerve growth factor mediated neuronal differentiation.
== Classification == There are two kinds of enamel proteins: amelogenins and nonamelogenins. Tuftelin falls under nonamelogenins.