amine

Also known as amines

AI overview

Amines are organic compounds containing carbon-nitrogen bonds that form when hydrogen atoms in ammonia are replaced by other carbon-containing groups. They are important in chemistry because they appear widely in nature and are used to create many useful substances, from pharmaceuticals to industrial materials.

AI-generated from the Wikipedia summary — may contain errors.

Research

1,166,239 papers

Amine coupling through EDC/NHS: a practical approach.Methods in molecular biology (Clifton, N.J.) · 2010Fischer MJDOI: 10.1007/978-1-60761-670-2_3
Unprotected amine transfer performed by non-heme iron(II) complexes.Chemical communications (Cambridge, England) · 2022Boullé A, Doumbia A, Mahy JP et al.DOI: 10.1039/d2cc04992a
Amine dehydrogenases: a versatile class of enzymes in the asymmetric synthesis of chiral amines and amino alcohols.ReviewChemical communications (Cambridge, England) · 2026Zhu HY, Ma YM, Gu QS et al.DOI: 10.1039/d6cc01143h
Biocatalytic concepts for synthesizing amine bulk chemicals: recent approaches towards linear and cyclic aliphatic primary amines and ω-substituted derivatives thereof.ReviewApplied microbiology and biotechnology · 2019Gröger HDOI: 10.1007/s00253-018-9452-0
Structure and Mutation of the Native Amine Dehydrogenase MATOUAmDH2.Chembiochem : a European journal of chemical biology · 2022Bennett M, Ducrot L, Vergne-Vaxelaire C et al.DOI: 10.1002/cbic.202200136
Advances in the Catalytic Reductive Amination of Furfural to Furfural Amine: The Momentous Role of Active Metal Sites.ReviewChemSusChem · 2022Saini MK, Kumar S, Li H et al.DOI: 10.1002/cssc.202200107
A Multiplex Assay to Assess the Transaminase Activity toward Chemically Diverse Amine Donors.Chembiochem : a European journal of chemical biology · 2023Czarnievicz N, Rubanu MG, Iturralde M et al.DOI: 10.1002/cbic.202200614
Catalytic asymmetric addition of an amine N-H bond across internal alkenes.Nature · 2020Xi Y, Ma S, Hartwig JFDOI: 10.1038/s41586-020-2919-z

via PubMed

Wikidata facts

Show 2 more facts

SMARTS notation: [NX3;H2,H1;!$(NC=O)]
Commons category: Amines

Sources (2)

via Wikidata · CC0

~22 min read

Article

34 sections

Contents

Classification of amines
Related compounds
Naming conventions
Physical properties
Spectroscopic identification
Structure
Alkyl amines
Aromatic amines
Basicity
Electronic effects
Solvation effects
Synthesis
From alcohols
From alkyl and aryl halides
From alkenes
Reductive routes
Specialized methods
Reactions
Alkylation, acylation, and sulfonation, etc.
Diazotization
Conversion to imines
Overview
Biological activity
Amine hormones
Application of amines
Dyes
Drugs
Gas treatment
Epoxy resin curing agents
Safety
See also
References
Further reading
External links

thumb|164x164px|Primary amine In chemistry, amines (, ) are organic compounds that contain carbon–nitrogen bonds. Amines are formed when one or more hydrogen atoms in ammonia are replaced by alkyl or aryl groups. The nitrogen atom in an amine possesses a lone pair of electrons. Amines can also exist as heterocyclic compounds. Aniline is the simplest aromatic amine, consisting of a benzene ring bonded to an amino group. thumb|3D diagram of the aromatic compound of aniline. The light black balls are carbon atoms, and white balls are hydrogen atoms, while the nitrogen atom is the blue ball. The dots in carbon bonds represent localization of electrons. Amines are classified into three types: primary (1°), secondary (2°), and tertiary (3°) amines. Primary amines (1°) contain one alkyl or aryl substituent and have the general formula RNH2. Secondary amines (2°) have two alkyl or aryl groups attached to the nitrogen atom, with the general formula R2NH. Tertiary amines (3°) contain three substituent groups bonded to the nitrogen atom, and are represented by the formula R3N.

The functional group present in primary amines is called the amino group.