File:Amiodarone_structure.svg · Wikimedia Commons · See Wikimedia Commons
amiodarone
Sign in to saveAlso known as amiodarone hydrochloride, Cordarone®, 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran, 2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone, 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran, Amiodaronum, Amiodarona
Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of cardiac dysrhythmias. This includes ventricular tachycardia, ventricular fibrillation, and wide complex tachycardia, atrial fibrillation, and paroxysmal supraventricular tachycardia. Evidence of benefit for cardiac arrest is poor. It can be given by mouth, intravenously, or intraosseously. When used by mouth, it can take a few weeks for effects to begin.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 464394155
- Drug.image
- Amiodarone structure.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Amiodarone-based-on-hydrochloride-xtal-3D-bs-17.png
- Drug.image_class2
- bg-transparent
- Drug.pronounce
- or
- Drug.tradename
- Cordarone, Nexterone, Pacerone, others
- Drug.MedlinePlus
- a687009
- Drug.DailyMedID
- Amiodarone
- Drug.pregnancy_AU
- C
- Drug.routes_of_administration
- By mouth, intravenous, intraosseous
- Drug.ATC_prefix
- C01
- Drug.ATC_suffix
- BD01
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
- Drug.legal_US
- Rx-only
- Drug.bioavailability
- 20–55%
via Wikipedia infobox
Chemical data
- Formula
- C25H29I2NO3
- Molecular weight
- 645.3 g/mol
- IUPAC name
- (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone
- SMILES
- CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I
- InChIKey
- IYIKLHRQXLHMJQ-UHFFFAOYSA-N
- XLogP
- 7.6
- Polar surface area
- 42.7 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
12,944 papers- Acute Amiodarone Pulmonary Toxicity.Journal of cardiothoracic and vascular anesthesia · 2021
- Amiodarone-induced thyreopaties.Casopis lekaru ceskych · 2025
- Amiodarone.The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society · 1989
- Amiodarone and the thyroid.The American journal of medicine · 2005
- Amiodarone.The New England journal of medicine · 1987
via PubMed
Wikidata facts
- Mass
- 645.024
Show 3 more facts
- Commons category
- Amiodarone
- chemical formula
- C₂₅H₂₉I₂NO₃
- canonical SMILES
- CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I
via Wikidata · CC0
~32 min read
Article
21 sectionsContents
- Medical uses
- Cardiac arrest
- Ventricular tachycardia
- Atrial fibrillation
- Contraindications
- Side effects
- Lung
- Thyroid
- Eye
- Liver
- Skin
- Pregnancy and breastfeeding
- Other
- Drug-drug interactions
- Metabolism
- Excretion
- Pharmacology
- History
- Name
- Dosing
- References
{{Infobox drug | Watchedfields = changed | verifiedrevid = 464394155 | image = Amiodarone structure.svg | image_class = skin-invert-image | alt = | image2 = Amiodarone-based-on-hydrochloride-xtal-3D-bs-17.png | image_class2 = bg-transparent | alt2 =
| pronounce = or | tradename = Cordarone, Nexterone, Pacerone, others | Drugs.com = | MedlinePlus = a687009 | DailyMedID = Amiodarone | pregnancy_AU = C | pregnancy_category = | routes_of_administration = By mouth, intravenous, intraosseous | ATC_prefix = C01 | ATC_suffix = BD01