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aptamer
EntityQ418722· pop 23· linked from 109 articles

thumb|425x170 px|Left: Unbound aptamer. Right: the aptamer bound to its target protein. The protein is in yellow. Parts of the aptamer that change shape when it binds its target are in blue, while the unchanging parts are in orange. The parts of the aptamer that contact the protein are highlighted in red.

~21 min read

Article

18 sections
Contents
  • Etymology
  • Classification
  • History
  • Properties
  • Structure
  • Targets
  • Antibody replacement
  • Controlled release of therapeutics
  • Tissue Engineering Application
  • AptaBiD
  • Peptide Aptamers
  • Structure
  • Selection
  • Applications
  • Industry and Research Community
  • See also
  • References
  • Further reading

thumb|425x170 px|Left: Unbound aptamer. Right: the aptamer bound to its target protein. The protein is in yellow. Parts of the aptamer that change shape when it binds its target are in blue, while the unchanging parts are in orange. The parts of the aptamer that contact the protein are highlighted in red.

thumb|450x330 px|Breast cancer cells incubated with aptamers that bind selectively to [[biomarkers on the cancer cells, but not to healthy cells. Aptamers are linked to Alexa Fluor 594, a molecule that glows red under UV light. This type of test allows a doctor or researcher to identify cancer cells in a tissue sample from a patient.]]

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