ARHGDIB

Name

Rho GDP dissociation inhibitor beta

Type

protein-coding

Position

14,942,009–14,961,985 (−)

Aliases

D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2

Ensembl

ENSG00000111348

RefSeq RNA

NM_001175.7, NM_001321420.2, NM_001321421.2, NM_001321422.1, NM_001321423.1

RefSeq protein

NP_001166.3, NP_001308349.1, NP_001308350.1, NP_001308351.1, NP_001308352.1

Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM, Dec 2010].

via MyGene.info

Gene · Ensembl

Rho GDP dissociation inhibitor beta

Symbol

ARHGDIB

Biotype

Protein coding

Organism

Homo sapiens

Location

12:14,942,009-14,961,985

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Rho GDP-dissociation inhibitor 2 - 5H1D.png

via Wikidata · CC0