artemether

Also known as Artemetheri, beta-Artemether, (1R,4S,5R,8S,9R,10S,12R,13R)-10-Methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane, Dihydroqinghaosu methyl ether, Artemisininelactol methyl ether, Methyl-dihydroartemisinine, Artemetero, SM-224

Artemether is a medication used for the treatment of malaria. The injectable form is specifically used for severe malaria rather than quinine. In adults, it may not be as effective as artesunate. It is given by injection in a muscle. It is also available by mouth in combination with lumefantrine, known as artemether/lumefantrine.

Key facts

Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.verifiedrevid: 457818137
Drug.IUPAC_name: (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]-2-benzopyran
Drug.image: artemether.svg
Drug.image_class: skin-invert-image
Drug.width: 150
Drug.image2: Artemether ball-and-stick model from xtal 2007.png
Drug.image_class2: bg-transparent
Drug.width2: 200
Drug.tradename: Many
Drug.pregnancy_US: C

Article

8 sections

Contents

Medical uses
Side effects
Drug interactions
Pharmacology
Mechanism of action
Pharmacokinetics
Chemistry
References

Artemether causes relatively few side effects. An irregular heartbeat may rarely occur. While there is evidence that use during pregnancy may be harmful in animals, there is no evidence of concern in humans. The World Health Organization (WHO) therefore recommends its use during pregnancy. It is in the artemisinin class of medication.