artesunate
Also known as Arsumax, artesunato, artesunatum, artesunic acid, AS, butanedioic acid, 1-[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester, dihydroqinghasu hemsuccinate
Artesunate is a medication used to treat malaria. The intravenous form is preferred to quinine for severe malaria. Often it is used as part of combination therapy, such as artesunate plus mefloquine. It is not used for the prevention of malaria. Artesunate can be given by injection into a vein, injection into a muscle, by mouth, and by rectum.
Key facts
- Drug.image
- Artesunate.svg
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 457818909
- Drug.image_class
- skin-invert-image
- Drug.image2
- Artesunate ball-and-stick model from xtal 2002.png
- Drug.image_class2
- bg-transparent
- Drug.pronounce
- ahr-tez′ŭ-nāt
- Drug.tradename
- many
- Drug.DailyMedID
- Artesunate
- Drug.routes_of_administration
- By mouth, intravenous, intramuscular
- Drug.class
- Artemisinin
~10 min read
Article
12 sectionsContents
- Medical uses
- Pregnancy
- Children
- Adverse effects
- Contraindications
- Mechanisms of action
- Pharmacokinetics
- Chemical synthesis
- Research
- History
- References
- External links
Artesunate is a medication used to treat malaria. The intravenous form is preferred to quinine for severe malaria. Often it is used as part of combination therapy, such as artesunate plus mefloquine. It is not used for the prevention of malaria. Artesunate can be given by injection into a vein, injection into a muscle, by mouth, and by rectum.
The most common side effects include kidney failure requiring dialysis, hemoglobinuria (the presence of hemoglobin in urine) and jaundice.
Connections
Categories
Antimalarial agentsCarboxylate estersCarboxylic acidsChemical articles with multiple CAS registry numbersChemical articles with multiple PubChem CIDsChemicals using indexlabelsDrugboxes which contain changes to verified fieldsDrugboxes which contain changes to watched fieldsDrugs with non-standard legal statusECHA InfoCard ID from WikidataHeterocyclic compounds with 4 rings