ASCC3

Also known as ASC1p200, HELIC1, RNAH, activating signal cointegrator 1 complex subunit 3

Activating signal cointegrator 1 complex subunit 3 is a protein that in humans is encoded by the ASCC3 gene.

Gene data

ASCC3

Name: activating signal cointegrator 1 complex subunit 3
Type: protein-coding
Position: 100,508,194–100,881,407 (−)
Aliases: ASC1p200, HELIC1, MRT81, RNAH
Ensembl: ENSG00000112249
RefSeq RNA: NM_001284271.2, NM_006828.4, NM_022091.5, XM_011535394.4, XM_047418107.1
RefSeq protein: NP_001271200.1, NP_006819.2, NP_071374.1, XP_011533696.1, XP_047274063.1

This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013].