File:Blausen_0657_MultipolarNeuron.png · Wikimedia Commons · See Wikimedia Commons
axon
Sign in to saveAlso known as GO:0030424, axons, nerve fiber
An axon (from ; also called a nerve fiber or fibre) is a long slender projection of a nerve cell or neuron found in most animals that typically conducts electrical impulses known as action potentials away from the nerve cell body. The function of the axon is to transmit information to different neurons, muscles, and glands. In certain sensory neurons (pseudounipolar neurons), such as those for touch and warmth, the axons are called afferent nerve fibers and the electrical impulse travels along these from the periphery to the cell body and from the cell body to the spinal cord along another bra
An axon is a long, thin extension of a nerve cell that conducts electrical signals away from the nerve cell body to transmit information to other neurons, muscles, and glands. These structures are essential for communication throughout the nervous system, allowing your body to process sensations and coordinate responses.
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Key facts
- Anatomy.name
- Axon
- Anatomy.image
- Blausen 0657 MultipolarNeuron.png
- Anatomy.caption
- An axon of a multipolar neuron
via Wikipedia infobox
Research
134,092 papers- Axon guidance receptors: Endocytosis, trafficking and downstream signaling from endosomes.ReviewProgress in neurobiology · 2021Pasterkamp RJ, Burk KDOI: 10.1016/j.pneurobio.2020.101916
- Axon guidance during mouse central nervous system regeneration is required for specific brain innervation.Developmental cell · 2024Delpech C, Schaeffer J, Vilallongue N et al.DOI: 10.1016/j.devcel.2024.09.005
- Axon death signalling in Wallerian degeneration among species and in disease.ReviewOpen biology · 2019Llobet Rosell A, Neukomm LJDOI: 10.1098/rsob.190118
- Mechanisms of axon polarization in pyramidal neurons.ReviewMolecular and cellular neurosciences · 2020Arikkath JDOI: 10.1016/j.mcn.2020.103522
- Molecular regulation of axon termination in mechanosensory neurons.ReviewDevelopment (Cambridge, England) · 2024Desbois M, Grill BDOI: 10.1242/dev.202945
- Axon guidance proteins in neurological disorders.ReviewThe Lancet. Neurology · 2015Van Battum EY, Brignani S, Pasterkamp RJDOI: 10.1016/S1474-4422(14)70257-1
- Axon degeneration: context defines distinct pathways.ReviewCurrent opinion in neurobiology · 2016Geden MJ, Deshmukh MDOI: 10.1016/j.conb.2016.05.002
- Axon guidance and somites.ReviewCell and tissue research · 1997Tannahill D, Cook GM, Keynes RJDOI: 10.1007/s004410050932
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Wikidata facts
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- Axons
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- purl.obolibrary.org/obo/GO_0030424
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~32 min read
Article
27 sectionsContents
- Anatomy
- Axonal region
- Axon hillock
- Axonal initial segment
- Axonal transport
- Myelination
- Nodes of Ranvier
- Axon terminals
- Axonal varicosities
- Action potentials
- Development and growth
- Development
- Extracellular signaling
- Intracellular signaling
- Cytoskeletal dynamics
- Growth
- Length regulation
- Classification
- Autonomic
- Clinical significance
- Terminology
- History
- Other animals
- Additional images
- See also
- References
- External links
An axon (from ; also called a nerve fiber or fibre) is a long slender projection of a nerve cell or neuron found in most animals that typically conducts electrical impulses known as action potentials away from the nerve cell body. The function of the axon is to transmit information to different neurons, muscles, and glands. In certain sensory neurons (pseudounipolar neurons), such as those for touch and warmth, the axons are called afferent nerve fibers and the electrical impulse travels along these from the periphery to the cell body and from the cell body to the spinal cord along another branch of the same axon. Axon dysfunction can be the cause of many inherited and many acquired neurological disorders that affect both the peripheral and central neurons. Nerve fibers are classed into three typesgroupA nerve fibers, groupB nerve fibers, and groupC nerve fibers. GroupsA andB are myelinated, and groupC is unmyelinated. These groups include both sensory fibers and motor fibers. Another classification groups only the sensory fibers into four categories: TypeI, TypeII, TypeIII, and TypeIV.
An axon is one of two types of cytoplasmic protrusions from the cell body of a neuron; the other type is a dendrite. Axons are distinguished from dendrites by several features, including shape (dendrites often taper while axons usually maintain a constant radius), length (dendrites are restricted to a small region around the cell body while axons can be much longer), and function (dendrites receive signals whereas axons transmit them). Some types of neurons have no axon and transmit signals from their dendrites. In some species, axons can emanate from dendrites known as axon-carrying dendrites. No neuron ever has more than one axon; however, in invertebrates such as insects or leeches, the axon sometimes consists of several regions that function more or less independently of each other.
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