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benzofuranylpropylaminopentane

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EntityQ4890795· pop 5· linked from 1,050 articles

benzofuranylpropylaminopentane

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Also known as (-)-BPAP

(–)-Benzofuranylpropylaminopentane (BPAP; developmental code name FPFS-1169) is an experimental drug related to selegiline which acts as a monoaminergic activity enhancer (MAE). It is orally active in animals.

In the Vinony graph

Within Vinony's link graph, benzofuranylpropylaminopentane is referenced by 1,050 other articles, and connects out to route of administration, monoamine oxidase inhibitor and lysergic acid diethylamide.

It is catalogued under topics including Anti-aging substances, Antidepressants and Antiparkinsonian agents.

Its subject is documented across 4 Wikipedia language editions.

Chemical data

Formula
C16H23NO
Molecular weight
245.36 g/mol
IUPAC name
1-(1-benzofuran-2-yl)-N-propylpentan-2-amine
SMILES
CCCC(CC1=CC2=CC=CC=C2O1)NCCC
InChIKey
LJHIBIVAYHQPBT-UHFFFAOYSA-N
XLogP
4.4
Polar surface area
25.2 Ų
H-bond donors
1
H-bond acceptors
2
Formal charge
0

via PubChem

Wikidata facts

Mass
245.177964356
Show 3 more facts
chemical formula
C₁₆H₂₃NO
canonical SMILES
CCCC(CC1=CC2=CC=CC=C2O1)NCCC
Commons category
Benzofuranylpropylaminopentane

via Wikidata · CC0

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Encyclopedic overview

11 sections
Contents
  • Pharmacology
  • Pharmacodynamics
  • Monoaminergic activity enhancer
  • Other actions
  • Pharmacokinetics
  • Chemistry
  • History
  • Research
  • See also
  • References
  • External links

(–)-Benzofuranylpropylaminopentane (BPAP; developmental code name FPFS-1169) is an experimental drug related to selegiline which acts as a monoaminergic activity enhancer (MAE). It is orally active in animals.

BPAP is a highly potent MAE and enhances the nerve impulse propagation-mediated release of serotonin, norepinephrine, and dopamine. At much higher concentrations, BPAP is also a monoamine reuptake inhibitor, specifically of dopamine and norepinephrine and to a much lesser extent of serotonin. BPAP produces psychostimulant-like effects in animals, with these effects mediated by its MAE actions. The drug is a substituted benzofuran derivative and tryptamine relative structurally related to phenylpropylaminopentane (PPAP).

Excerpted from Wikipedia’s “benzofuranylpropylaminopentane” article, available under the CC BY-SA 4.0 licence.

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