benzphetamine
Sign in to saveAlso known as (S)-(+)-N-benzyl-N,α-dimethylphenethylamine, N-methyl-1-phenyl-N-(phenylmethyl)propan-2-amine, (S)-benzphetamine, d-N-methyl-N-benzyl-β-phenylisopropylamine, (+)-N-benzyl-N,α-dimethylphenethylamine, (+)-benzphetamine, (+)-N,α-dimethyl-N-(phenylmethyl)-benzeneethanamine, (S)-(+)-benzphetamine
Benzphetamine, sold under the brand name Didrex among others, is an amphetamine-type stimulant and appetite suppressant used short-term for weight loss along with a doctor-approved, reduced-calorie diet, exercise, and behavioral program. It is prescribed for obesity to people who have been unable to lose weight through exercise and dieting alone. It is a prodrug of dextromethamphetamine and dextroamphetamine.
Research
992 papers- Exploring the Theoretical Potential of Benzphetamine in the Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD).Cureus · 2025
- Role of d-amphetamine and d-methamphetamine as active metabolites of benzphetamine: Evidence from drug discrimination and pharmacokinetic studies in male rhesus monkeys.Pharmacology, biochemistry, and behavior · 2017
- Comparison table: Some drugs for weight management.The Medical letter on drugs and therapeutics · 2025
- Development of a method for the quantitation of benzphetamine metabolites in human urine by high-performance liquid chromatography.Annals of clinical biochemistry · 1998
- A case of benzphetamine poisoning.The American journal of forensic medicine and pathology · 1982
via PubMed
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Encyclopedic overview
8 sectionsContents
- Mechanism of Action
- Contraindications
- Pharmacology
- Society and culture
- Names
- Legal status
- United States
- References
Benzphetamine, sold under the brand name Didrex among others, is an amphetamine-type stimulant and appetite suppressant used short-term for weight loss along with a doctor-approved, reduced-calorie diet, exercise, and behavioral program. It is prescribed for obesity to people who have been unable to lose weight through exercise and dieting alone. It is a prodrug of dextromethamphetamine and dextroamphetamine.
==Mechanism of Action== Benzphetamine promotes weight loss by reducing appetite and slightly increasing metabolism. It is the parent compound of clobenzorex, the latter of which is not subject to the Federal Analogue Act, nor scheduled per the Controlled Substances Act of 1970.
Excerpted from Wikipedia’s “benzphetamine” article, available under the CC BY-SA 4.0 licence.