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bexagliflozin

Structure via PubChem · Public domain (PubChem)

EntityQ27277423· pop 9· linked from 34 articles

bexagliflozin

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Bexagliflozin, sold under the brand name Brenzavvy, is an antidiabetic medication used to improve glycemic control in adults with type 2 diabetes. It is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that is taken by mouth.

In the Vinony graph

Within Vinony's link graph, bexagliflozin is referenced by 34 other articles, and connects out to metformin, anti-diabetic medication and alogliptin.

Vinony files it under Cat medications, Chloroarenes and Cyclopropyl compounds.

Its subject is documented across 8 Wikipedia language editions.

Chemical data

Formula
C24H29ClO7
Molecular weight
464.9 g/mol
IUPAC name
(2S,3R,4R,5S,6R)-2-[4-chloro-3-[[4-(2-cyclopropyloxyethoxy)phenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
SMILES
C1CC1OCCOC2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl
InChIKey
BTCRKOKVYTVOLU-SJSRKZJXSA-N
XLogP
2.4
Polar surface area
109 Ų
H-bond donors
4
H-bond acceptors
7
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Approved
Molecule type
Small molecule
First approval
2023
Admin. routes
oral
Indications
diabetes mellitus, essential hypertension, type 2 diabetes mellitus

via ChEMBL · EBI

Wikidata facts

Instance of
gliflozins
Mass
464.16
Show 5 more facts
canonical SMILES
C1CC1OCCOC2=CC=C(C=C2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)Cl
chemical formula
C₂₄H₂₉ClO₇
isomeric SMILES
C1CC1OCCOC2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl
subject has role
veterinary drug
Commons category
Bexagliflozin
Sources (1)

via Wikidata · CC0

~6 min read

Encyclopedic overview

10 sections
Contents
  • Medical uses
  • Adverse effects
  • History
  • Society and culture
  • Legal status
  • Research
  • Veterinary uses
  • References
  • Further reading
  • External links

{{Infobox drug | image = Bexagliflozin structure.svg | image_class = skin-invert-image | width = 325 | alt = | caption =

| pronounce = | tradename = Brenzavvy, Bexacat | Drugs.com = | MedlinePlus = a623027 | DailyMedID = Bexagliflozin | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = By mouth | class = | ATC_prefix = A10 | ATC_suffix = BK08 | ATC_supplemental =

Excerpted from Wikipedia’s “bexagliflozin” article, available under the CC BY-SA 4.0 licence.

Available in 8 languages

via Wikidata sitelinks · CC0

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