Structure via PubChem · Public domain (PubChem)
ipragliflozin
Sign in to saveAlso known as C21H21FO5S
Ipragliflozin (INN, trade names Suglat) is a pharmaceutical drug for treatment of type 2 diabetes. Ipragliflozin, jointly developed by Astellas Pharma and Kotobuki Pharmaceutical, was approved in Japan on January 17, 2014, and in Russia on May 22, 2019.
Chemical data
- Formula
- C21H21FO5S
- Molecular weight
- 404.5 g/mol
- IUPAC name
- (2S,3R,4R,5S,6R)-2-[3-(1-benzothiophen-2-ylmethyl)-4-fluorophenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
- SMILES
- C1=CC=C2C(=C1)C=C(S2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)F
- InChIKey
- AHFWIQIYAXSLBA-RQXATKFSSA-N
- XLogP
- 2.5
- Polar surface area
- 118 Ų
- H-bond donors
- 4
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2013
- Admin. routes
- oral
- Indications
- diabetes mellitus, type 1 diabetes mellitus, type 2 diabetes mellitus
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 404.109
Show 5 more facts
- chemical formula
- C₂₁H₂₁FO₅S
- isomeric SMILES
- C1=CC=C2C(=C1)C=C(S2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)F
- Commons category
- Ipragliflozin
- canonical SMILES
- C1=CC=C2C(=C1)C=C(S2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)F
- subject has role
- gliflozins
Sources (2)
via Wikidata · CC0
~6 min read
Encyclopedic overview
5 sectionsContents
- Clinical trials
- Commercialization
- Marketing
- Intellectual Property
- References
{{Infobox drug | drug_name = | IUPAC_name = (2S,3R,4R,5S,6R)-2-{3-[(1-benzothiophen-2-yl)methyl]-4-fluorophenyl}-6-(hydroxymethyl)oxane-3,4,5-triol | image = Ipragliflozin structure.svg | image_class = skin-invert-image | width = 275 | image2 = Haworth projection of ipragliflozin.svg | image_class2 = skin-invert-image | width2 = 225 | caption = Haworth projection (bottom)
| tradename = Suglat | Drugs.com = | MedlinePlus = | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_AU_comment = | legal_CA = | legal_NZ = | legal_UK = | legal_US_comment = Not available | legal_UN = | legal_status = Rx-only (JP) | routes_of_administration = By mouth (tablets)
Excerpted from Wikipedia’s “ipragliflozin” article, available under the CC BY-SA 4.0 licence.