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GeneQ18039621· pop 5· linked from 7 articles

BRD7

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Also known as BP75, CELTIX1, NAG4, bromodomain containing 7, SMARCI1

Bromodomain-containing protein 7 is a protein that in humans is encoded by the BRD7 gene.

Gene data

BRD7
Name
bromodomain containing 7
Type
protein-coding
Position
50,313,487–50,369,059 (−)
Aliases
BP75, CELTIX1, NAG4, SMARCI1
Ensembl
ENSG00000166164
RefSeq RNA
NM_001173984.4, NM_001437990.1, NM_001438173.1, NM_001438174.1, NM_001438175.1
RefSeq protein
NP_001167455.1, NP_001424919.1, NP_001425102.1, NP_001425103.1, NP_001425104.1

This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010].

Gene Ontology

Pathways

Hepatocellular carcinoma - Homo sapiens (human)Generic Transcription PathwayTranscriptional Regulation by TP53Chromatin organizationRegulation of TP53 ActivityRegulation of TP53 Activity through AcetylationRNA Polymerase II TranscriptionGene expression (Transcription)ATP-dependent chromatin remodelersSWI/SNF chromatin remodelers

via MyGene.info

Gene · Ensembl

bromodomain containing 7

Symbol
BRD7
Biotype
Protein coding
Organism
Homo sapiens
Location
16:50,313,487-50,369,059
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
8085
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/29117
genomic end
50368988
genomic start
50347398
chromosome
human chromosome 16
cytogenetic location
16q12.1
expressed in
popliteal artery
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

5 sections
Contents
  • Interactions
  • [[Azoospermia]]
  • References
  • External links
  • Further reading

Bromodomain-containing protein 7 is a protein that in humans is encoded by the BRD7 gene.

==Interactions== BRD7 has been shown to interact with IRF2 and HNRPUL1.

Excerpted from Wikipedia’s “BRD7” article, available under the CC BY-SA 4.0 licence.

Available in 4 languages

via Wikidata sitelinks · CC0