Structure via PubChem · Public domain (PubChem)
butoconazole
Sign in to saveAlso known as Femstat, 1-[4-(4-Chloro-phenyl)-2-(2,6-dichloro-phenylsulfanyl)-butyl]-1H-imidazole, Alant starch, Polyfructosanum, Compositenstärke, Dahlin, Butoconazol
Butoconazole (trade names Gynazole-1, Mycelex-3) is an imidazole antifungal used in gynecology. It is administered as a vaginal cream.
Chemical data
- Formula
- C19H17Cl3N2S
- Molecular weight
- 411.8 g/mol
- IUPAC name
- 1-[4-(4-chlorophenyl)-2-(2,6-dichlorophenyl)sulfanylbutyl]imidazole
- SMILES
- C1=CC(=C(C(=C1)Cl)SC(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3)Cl
- InChIKey
- SWLMUYACZKCSHZ-UHFFFAOYSA-N
- XLogP
- 6.4
- Polar surface area
- 43.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1985
- Admin. routes
- topical
via ChEMBL · EBI
Research
73 papers- Butoconazole.2006
- Butoconazole nitrate.Infection control and hospital epidemiology · 1988
- N-Methylfulleropyrrolidine-Based Multimode Sensor for Determination of Butoconazole Nitrate.ACS omega · 2022
- Butoconazole for vulvovaginal candidiasis.The Medical letter on drugs and therapeutics · 1986
- Butoconazole and miconazole in treating vaginal candidiasis.Genitourinary medicine · 1985
via PubMed
Wikidata facts
- Subclass of
- azole
- Mass
- 410.017803
- Has use
- medication
Show 7 more facts
- subject has role
- antifungal
- chemical formula
- C₁₉H₁₇Cl₃N₂S
- Commons category
- Butoconazole
- medical condition treated
- vulvovaginal candidiasis
- canonical SMILES
- C1=CC(=C(C(=C1)Cl)SC(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3)Cl
- World Health Organisation international non-proprietary name
- butoconazole
- defined daily dose
- 0.1
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
Butoconazole (trade names Gynazole-1, Mycelex-3) is an imidazole antifungal used in gynecology. It is administered as a vaginal cream.
== References ==
Excerpted from Wikipedia’s “butoconazole” article, available under the CC BY-SA 4.0 licence.