CAB39
Sign in to saveAlso known as MO25, CGI-66, calcium binding protein 39
Calcium-binding protein 39 is a protein that in humans is encoded by the CAB39 gene.
Gene data
CAB39- Name
- calcium binding protein 39
- Type
- protein-coding
- Position
- 230,712,822–230,821,076 (+)
- Aliases
- CGI-66, MO25
- Ensembl
- ENSG00000135932
- RefSeq RNA
- NM_001130849.2, NM_001130850.2, NM_016289.4, XR_007076406.1, XR_007076407.1
- RefSeq protein
- NP_001124321.1, NP_001124322.1, NP_057373.1
Enables kinase binding activity and protein serine/threonine kinase activator activity. Involved in intracellular signal transduction; peptidyl-serine phosphorylation; and positive regulation of protein phosphorylation. Located in extracellular exosome. Implicated in hepatocellular carcinoma. Biomarker of hepatocellular carcinoma and pancreatic cancer. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
calcium binding protein 39
- Symbol
- CAB39
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:230,712,822-230,821,086
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CAB39 PDB 1upk.png
Show 5 more facts
- HomoloGene ID
- 69212
- exact match
- identifiers.org/ncbigene/51719
- genomic end
- 231685790
- genomic start
- 230712842
- cytogenetic location
- 2q37.1
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- References
- External links
- Further reading
Calcium-binding protein 39 is a protein that in humans is encoded by the CAB39 gene.
The protein encoded by this gene associates with STK11 (Serine/Threonine Kinase 11) and STRAD (STE20-Related ADaptor protein). CAB39 enhances formation of STK11/STRAD complexes and stimulates STK11 catalytic activity. CAB39 may function as a scaffolding component of the STK11/STRAD complex and regulates STK11 activity and cellular localization.