CAB39

Also known as MO25, CGI-66, calcium binding protein 39

Calcium-binding protein 39 is a protein that in humans is encoded by the CAB39 gene.

Gene data

CAB39

Name: calcium binding protein 39
Type: protein-coding
Position: 230,712,822–230,821,076 (+)
Aliases: CGI-66, MO25
Ensembl: ENSG00000135932
RefSeq RNA: NM_001130849.2, NM_001130850.2, NM_016289.4, XR_007076406.1, XR_007076407.1
RefSeq protein: NP_001124321.1, NP_001124322.1, NP_057373.1

Enables kinase binding activity and protein serine/threonine kinase activator activity. Involved in intracellular signal transduction; peptidyl-serine phosphorylation; and positive regulation of protein phosphorylation. Located in extracellular exosome. Implicated in hepatocellular carcinoma. Biomarker of hepatocellular carcinoma and pancreatic cancer. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

response to activity regulation of transmembrane transport

Article

3 sections

Contents

References
External links
Further reading

Calcium-binding protein 39 is a protein that in humans is encoded by the CAB39 gene.

The protein encoded by this gene associates with STK11 (Serine/Threonine Kinase 11) and STRAD (STE20-Related ADaptor protein). CAB39 enhances formation of STK11/STRAD complexes and stimulates STK11 catalytic activity. CAB39 may function as a scaffolding component of the STK11/STRAD complex and regulates STK11 activity and cellular localization.