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cabotegravir
EntityQ15411012· pop 14· linked from 143 articles

cabotegravir

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Also known as GSK744

Cabotegravir, sold under the brand name Vocabria among others, is an antiretroviral medication used for the treatment and prevention of HIV/AIDS. It is available in the form of tablets and as an intramuscular injection, as well as in an injectable combination with rilpivirine under the brand name Cabenuva.

Key facts

Drug.image
Cabotegravir (GSK744).svg
Drug.image_class
skin-invert-image
Drug.image2
Cabotegravir ball-and-stick model.png
Drug.image_class2
bg-transparent
Drug.tradename
Vocabria, Apretude
Drug.MedlinePlus
a621010
Drug.DailyMedID
Cabotegravir
Drug.pregnancy_AU
B1
Drug.routes_of_administration
By mouth, intramuscular
Drug.ATC_prefix
J05
Drug.ATC_suffix
AJ04
Drug.legal_AU
S4
Drug.legal_CA
Rx-only
Drug.legal_US
Rx-only
Drug.legal_EU
Rx-only
Drug.protein_bound
>99%
Drug.metabolism
UGT1A1
Drug.metabolites
glucuronide

via Wikipedia infobox

~8 min read

Encyclopedic overview

16 sections
Contents
  • Medical uses
  • Contraindications and interactions
  • Adverse effects
  • Pharmacology
  • Mechanism of action
  • Pharmacokinetics
  • Pharmacogenomics
  • Chemistry
  • Formulation
  • History
  • Society and culture
  • Legal status
  • Names
  • Research
  • Pre-exposure prophylaxis
  • References

Cabotegravir, sold under the brand name Vocabria among others, is an antiretroviral medication used for the treatment and prevention of HIV/AIDS. It is available in the form of tablets and as an intramuscular injection, as well as in an injectable combination with rilpivirine under the brand name Cabenuva.

It is an integrase inhibitor with a carbamoyl pyridone structure similar to that of dolutegravir.

Excerpted from Wikipedia’s “cabotegravir” article, available under the CC BY-SA 4.0 licence.