stavudine
Also known as Zerit Xr, D4T, 1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine, 3'-Deoxy-2'-thymidinene, Sanilvudine, 2',3'-Didehydro-3'-deoxythimidine, STV, BMY-27857
Stavudine (d4T), sold under the brand name Zerit among others, is an antiretroviral medication used to prevent and treat HIV/AIDS. It is generally recommended for use with other antiretrovirals. It may be used for prevention after a needlestick injury or other potential exposure. However, it is not a first-line treatment. It is given by mouth.
Key facts
- Drug.verifiedrevid
- 477173315
- Drug.image
- Stavudine.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 180
- Drug.image2
- Stavudine ball-and-stick.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Zerit
- Drug.MedlinePlus
- a694033
- Drug.DailyMedID
- Stavudine
- Drug.pregnancy_AU
- B3
- Drug.routes_of_administration
- By mouth
- Drug.ATC_prefix
- J05
- Drug.ATC_suffix
~9 min read
Article
10 sectionsContents
- Medical uses
- Pregnancy and breastfeeding
- Children
- Elderly
- Adverse effects
- Mechanism of action
- Pharmacokinetics
- Drug interactions
- History
- References
Stavudine (d4T), sold under the brand name Zerit among others, is an antiretroviral medication used to prevent and treat HIV/AIDS. It is generally recommended for use with other antiretrovirals. It may be used for prevention after a needlestick injury or other potential exposure. However, it is not a first-line treatment. It is given by mouth.
Common side effects include headache, diarrhea, vomiting, rash, and peripheral nerve problems. Severe side effects include high blood lactate, pancreatitis, and an enlarged liver. It is not generally recommended in pregnancy. Stavudine is in the nucleoside analog reverse-transcriptase inhibitor (NRTI) class of medication.