CCNF
Sign in to saveAlso known as FBX1, FBXO1, cyclin F, FTDALS5
CCNF may also mean Canonical conjunctive normal form in Boolean algebra.
Gene data
CCNF- Name
- cyclin F
- Type
- protein-coding
- Aliases
- FBX1, FBXO1, FTDALS5
This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
cyclin F
- Symbol
- CCNF
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:2,429,394-2,458,913
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 1335
- genomic start
- 2479395
- exact match
- identifiers.org/ncbigene/899
- genomic end
- 2508855
- cytogenetic location
- 16p13.3
Sources (4)
via Wikidata · CC0
~6 min read
Article
15 sectionsContents
- Function
- Discovery and gene/protein characteristics
- Expression patterns
- Role
- RRM2
- CP110
- NuSAP
- SLBP
- E2F1, E2F2, and E2F3A
- Clinical significance
- Neurodegenerative diseases
- Cancer
- References
- Further reading
- External links
CCNF may also mean Canonical conjunctive normal form in Boolean algebra.
G2/mitotic-specific cyclin-F is a protein that in humans is encoded by the CCNF gene.