cyclin
Sign in to saveAlso known as IPR039361, Cyclin family, cyclins
thumb|Tertiary structure of human cyclin A (lacking the amino-terminal 170 amino acids), showing the central core of two five-helix bundles, with additional helices at the amino terminus (black) and carboxyl terminus (grey). The yellow region in helix 1 is the MRAIL sequence or hydrophobic patch, which contributes to the recognition of some substrates. (PDB 1fin)
Key facts
- Protein family.Symbol
- K-cyclin_vir_C
- Protein family.Name
- K cyclin, C terminal
- Protein family.image
- PDB 1g3n EBI.jpg
- Protein family.caption
- structure of a p18(ink4c)-cdk6-k-cyclin ternary complex
- Protein family.Pfam
- PF09080
- Protein family.Pfam_clan
- CL0065
- Protein family.InterPro
- IPR015164
- Protein family.PROSITE
- PDOC00264
- Protein family.SCOP
- 1g3n
- Protein family.PDB
- , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,
- Protein family.Prosite
- PDOC00264
via Wikipedia infobox
Research
97,880 papers- Less-well known functions of cyclin/CDK complexes.Seminars in cell & developmental biology · 2020
- The cyclin C/Cdk8 kinase.Progress in cell cycle research · 1996
- Cyclin E2, the cycle continues.The international journal of biochemistry & cell biology · 2002
- Cyclin D-dependent kinases, INK4 inhibitors and cancer.Biochimica et biophysica acta · 2002
- Cyclin/Cdk complexes: their involvement in cell cycle progression and mitotic division.Protoplasma · 2001
via PubMed
Wikidata facts
- Instance of
- protein family
- Image
- PDB 1vin EBI.jpg
Show 1 more fact
- Commons category
- Cyclins
via Wikidata · CC0
~9 min read
Encyclopedic overview
11 sectionsContents
- Etymology
- Function
- Domain structure
- Types
- Main groups
- Subtypes
- Other proteins containing this domain
- History
- References
- Further reading
- External links
thumb|Tertiary structure of human cyclin A (lacking the amino-terminal 170 amino acids), showing the central core of two five-helix bundles, with additional helices at the amino terminus (black) and carboxyl terminus (grey). The yellow region in helix 1 is the MRAIL sequence or hydrophobic patch, which contributes to the recognition of some substrates. (PDB 1fin)
Cyclins are proteins that control the progression of a cell through the cell cycle by activating cyclin-dependent kinases (CDK).
Excerpted from Wikipedia’s “cyclin” article, available under the CC BY-SA 4.0 licence.