GNAI1
Sign in to saveAlso known as Gi, G protein subunit alpha i1, HG1B, NEDHISB
Guanine nucleotide-binding protein G(i), alpha-1 subunit is a protein that in humans is encoded by the GNAI1 gene.
Gene data
GNAI1- Name
- G protein subunit alpha i1
- Type
- protein-coding
- Position
- 79,768,028–80,226,181 (+)
- Aliases
- Gi, HG1B, NEDHISB
- Ensembl
- ENSG00000127955
- RefSeq RNA
- NM_001256414.2, NM_002069.6
- RefSeq protein
- NP_001243343.1, NP_002060.4
Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. The protein encoded by this gene represents the alpha subunit of an inhibitory complex. The encoded protein is part of a complex that responds to beta-adrenergic signals by inhibiting adenylate cyclase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
G protein subunit alpha i1
- Symbol
- GNAI1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:79,768,028-80,226,181
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactive pathway map
- Interactions
- References
- Further reading
Guanine nucleotide-binding protein G(i), alpha-1 subunit is a protein that in humans is encoded by the GNAI1 gene.
== Interactive pathway map ==
Excerpted from Wikipedia’s “GNAI1” article, available under the CC BY-SA 4.0 licence.