RAC1
Sign in to saveAlso known as MIG5, Rac-1, TC-25, p21-Rac1, ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1), Rac family small GTPase 1, MRD48
Ras-related C3 botulinum toxin substrate 1, is a protein that in humans is encoded by the RAC1 gene. This gene can produce a variety of alternatively spliced versions of the Rac1 protein, which appear to carry out different functions.
Gene data
RAC1- Name
- Rac family small GTPase 1
- Type
- protein-coding
- Position
- 6,374,098–6,403,998 (+)
- Aliases
- MIG5, MRD48, Rac-1, TC-25, p21-Rac1
- Ensembl
- ENSG00000136238
- RefSeq RNA
- NM_006908.5, NM_018890.4, NM_198829.1
- RefSeq protein
- NP_008839.2, NP_061485.1
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
Rac family small GTPase 1
- Symbol
- RAC1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:6,374,098-6,404,016
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Ras-related C3 botulinum toxin substrate 1 8S1N.png
Show 6 more facts
- HomoloGene ID
- 69035
- exact match
- identifiers.org/ncbigene/5879
- genomic end
- 6403967
- genomic start
- 6374527
- cytogenetic location
- 7p22.1
- Commons category
- Rac1 GTP-binding protein
Sources (7)
via Wikidata · CC0
~4 min read
Article
10 sectionsContents
- Function
- Role in glucose transport
- Clinical significance
- Cancer
- Other diseases
- As a drug target
- Interactions
- References
- Further reading
- External links
Ras-related C3 botulinum toxin substrate 1, is a protein that in humans is encoded by the RAC1 gene. This gene can produce a variety of alternatively spliced versions of the Rac1 protein, which appear to carry out different functions.
== Function ==