GNAT1
Sign in to saveAlso known as CSNBAD3, GBT1, GNATR, CSNB1G, G protein subunit alpha transducin 1, HG1F
Guanine nucleotide-binding protein G(t) subunit alpha-1 is a protein that in humans is encoded by the GNAT1 gene.
Gene data
GNAT1- Name
- G protein subunit alpha transducin 1
- Type
- protein-coding
- Position
- 50,191,586–50,197,696 (+)
- Aliases
- CSNB1G, CSNBAD3, GBT1, GNATR, HG1F
- Ensembl
- ENSG00000114349
- RefSeq RNA
- NM_000172.4, NM_144499.3
- RefSeq protein
- NP_000163.2, NP_653082.1
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
G protein subunit alpha transducin 1
- Symbol
- GNAT1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:50,191,586-50,197,696
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- GNAT1-RGS9-PDE6G-complex 2 PDB 1fqj.png
Show 7 more facts
- HomoloGene ID
- 20084
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2779
- genomic end
- 50197696
- genomic start
- 50191610
- chromosome
- human chromosome 3
- cytogenetic location
- 3p21.31
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Guanine nucleotide-binding protein G(t) subunit alpha-1 is a protein that in humans is encoded by the GNAT1 gene.
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phosphodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. Alternative splicing of this gene results in two transcript variants.
Excerpted from Wikipedia’s “GNAT1” article, available under the CC BY-SA 4.0 licence.
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