GNG2

Also known as G protein subunit gamma 2

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 is a protein that in humans is encoded by the GNG2 gene.

Gene data

GNG2

Name: G protein subunit gamma 2
Type: protein-coding
Position: 51,826,195–51,979,342 (+)
Aliases: HG3F1
Ensembl: ENSG00000186469
RefSeq RNA: NM_001243773.2, NM_001243774.2, NM_001389707.1, NM_001389708.1, NM_001389709.1
RefSeq protein: NP_001230702.1, NP_001230703.1, NP_001376636.1, NP_001376637.1, NP_001376638.1

This gene encodes one of the gamma subunits of a guanine nucleotide-binding protein. Such proteins are involved in signaling mechanisms across membranes. Various subunits forms heterodimers which then interact with the different signal molecules. [provided by RefSeq, Aug 2011].

Gene Ontology

Biological process

G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway

Article

3 sections

Contents

Interactive pathway map
References
Further reading

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 is a protein that in humans is encoded by the GNG2 gene.

Heterotrimeric G proteins play vital roles in cellular responses to external signals. The specificity of a G protein-receptor interaction is primarily mediated by the gamma subunit.[supplied by OMIM]