GNG5
Sign in to saveAlso known as G protein subunit gamma 5
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 is a protein that in humans is encoded by the GNG5 gene.
Gene data
GNG5- Name
- G protein subunit gamma 5
- Type
- protein-coding
- Position
- 84,489,407–84,507,237 (−)
- Ensembl
- ENSG00000174021
- RefSeq RNA
- NM_005274.3
- RefSeq protein
- NP_005265.1
G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
G protein subunit gamma 5
- Symbol
- GNG5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:84,489,407-84,507,237
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 3861
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2787
- genomic end
- 84506581
- genomic start
- 84498323
- chromosome
- human chromosome 1
- cytogenetic location
- 1p22.3
- expressed in
- granulocyte
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 is a protein that in humans is encoded by the GNG5 gene.
==References==
Excerpted from Wikipedia’s “GNG5” article, available under the CC BY-SA 4.0 licence.