CDK2
Sign in to saveAlso known as cyclin-dependent kinase 2, A630093N05Rik, CDKN2, p33(CDK2), cyclin dependent kinase 2
protein-coding gene in the species Homo sapiens
Gene data
CDK2- Name
- cyclin dependent kinase 2
- Type
- protein-coding
- Position
- 55,966,781–55,972,789 (+)
- Aliases
- CDKN2, p33(CDK2)
- Ensembl
- ENSG00000123374
- RefSeq RNA
- NM_001290230.2, NM_001798.5, NM_052827.4, XM_011537732.2, XM_054370731.1
- RefSeq protein
- NP_001277159.1, NP_001789.2, NP_439892.2, XP_011536034.1, XP_054226706.1
This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cyclin dependent kinase 2
- Symbol
- CDK2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:55,966,781-55,972,789
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CDK2 PDB 1aq1.png
Show 5 more facts
- HomoloGene ID
- 74409
- exact match
- identifiers.org/ncbigene/1017
- genomic end
- 55972789
- genomic start
- 55966781
- cytogenetic location
- 12q13.2
via Wikidata · CC0