metaphase
Also known as GO:0051323
thumb|upright=1.35|The mitotic spindle checkpoint verifies that all the chromosomes are aligned properly on the metaphase plate and prevents premature entry into anaphase.
Research
26,428 papers- Metaphase-Based Cytogenetic Approach Identifies Radiation-Induced Chromosome and Chromatid Aberrations in Zebrafish Embryos.Radiation research · 2022
- How to Obtain High-Quality Metaphase Spreads for Molecular Cytogenetics.Current protocols · 2022
- The role of Fyn kinase in the release from metaphase in mammalian oocytes.Molecular and cellular endocrinology · 2010
- High Counts in Hematologic Malignancies Predict Low Metaphase Yield for Cytogenetic Analysis.American journal of clinical pathology · 2022
- Chromosome Recognition.Methods in molecular biology (Clifton, N.J.) · 2017
via PubMed
Wikidata facts
- Image
- Metaphase chromosomes.jpg
Sources (2)
Article
3 sectionsContents
- Metaphase in cytogenetics and cancer studies
- References
- External links
thumb|upright=1.35|The mitotic spindle checkpoint verifies that all the chromosomes are aligned properly on the metaphase plate and prevents premature entry into anaphase.
Metaphase ( and ) is a stage of mitosis in the cell cycle in which chromosomes of eukaryotes are at their second-most condensed and coiled stage (they are at their most condensed in anaphase). These chromosomes, carrying genetic information, align in the equator of the cell between the spindle poles at the metaphase plate, before being separated into each of the two daughter nuclei. This alignment marks the beginning of metaphase. Metaphase accounts for approximately 4% of the cell cycle's duration.