condensin complex
Also known as GO:0000796, Condensin
450px|thumb|Figure 1. An interphase nucleus (left) and a set of mitotic chromosomes (right) from human tissue culture cells. Bar, 10 μm. Condensins are large protein complexes that play a central role in chromosome condensation and segregation during mitosis and meiosis (Figure 1). Their subunits were originally identified as major components of mitotic chromosomes assembled in Xenopus egg extracts.
Research
1,180 papers- Condensin II activation by M18BP1.Molecular cell · 2025
- Establishment of dsDNA-dsDNA interactions by the condensin complex.Molecular cell · 2023
- Important role and underlying mechanism of non‑SMC condensin I complex subunit G in tumours (Review).Oncology reports · 2024
- A specialized condensin complex participates in somatic nuclear maturation in Tetrahymena thermophila.Molecular biology of the cell · 2019
- Condensin I folds the Caenorhabditis elegans genome.Nature genetics · 2024
via PubMed
~35 min read
Article
26 sectionsContents
- Subunit composition and phylogeny
- Eukaryotic types
- Prokaryotic types
- Molecular structures
- Molecular activities
- DNA compaction
- DNA supercoiling
- DNA loop extrusion
- DNA loop capture
- Chromosome assembly and reconstitution
- Condensin I vs condensin II
- Mathematical modeling and computer simulations
- Functions in chromosome assembly and segregation
- Mitosis
- Meiosis
- Chromosomal functions outside of mitosis or meiosis
- Regulation
- Spatiotemporal regulation
- Regulation by post-translational modifications
- Regulation by Short Linear Motifs (SLiMs)
- Regulation by proteolysis
- Relevance to diseases
- Evolutionary implications
- See also
- References
- External links
450px|thumb|Figure 1. An interphase nucleus (left) and a set of mitotic chromosomes (right) from human tissue culture cells. Bar, 10 μm. Condensins are large protein complexes that play a central role in chromosome condensation and segregation during mitosis and meiosis (Figure 1). Their subunits were originally identified as major components of mitotic chromosomes assembled in Xenopus egg extracts.
== Subunit composition and phylogeny ==