chromatin

Also known as GO:0000785

thumb|358x358px|The major structures in DNA compaction: DNA, the [[nucleosome, the 11 nm beads on a string chromatin fibre and the metaphase chromosome.]]

AI overview

Chromatin is the material made of DNA wound tightly around proteins, which allows the long strands of DNA to fit inside cells and be organized into a compact form. It matters because this packaging system controls which genes are accessible and active in a cell, influencing how cells function and develop.

AI-generated from the Wikipedia summary — may contain errors.

Research

168,959 papers

Chromatin control of human cytomegalovirus infection.ReviewmBio · 2023Matthews SM, Groves IJ, O'Connor CMDOI: 10.1128/mbio.00326-23
Chromatin's physical properties shape the nucleus and its functions.ReviewCurrent opinion in cell biology · 2019Stephens AD, Banigan EJ, Marko JFDOI: 10.1016/j.ceb.2019.02.006
Linking chromatin acylation mark-defined proteome and genome in living cells.Cell · 2023Qin F, Li B, Wang H et al.DOI: 10.1016/j.cell.2023.02.007
Progresses in the plant 3D chromatin architecture.ReviewYi chuan = Hereditas · 2020Dong QL, Wang JB, Li XC et al.DOI: 10.16288/j.yczz.19-326
Chromatin-mediated epigenetic regulation of HSV-1 transcription as a potential target in antiviral therapy.ReviewAntiviral research · 2021Schang LM, Hu M, Cortes EF et al.DOI: 10.1016/j.antiviral.2021.105103
Nucleosomes unwrapped: Structural perspectives on transcription through chromatin.ReviewCurrent opinion in structural biology · 2023Farnung LDOI: 10.1016/j.sbi.2023.102690
Customizing Host Chromatin: a Bacterial Tale.ReviewMicrobiology spectrum · 2019Connor M, Arbibe L, Hamon MDOI: 10.1128/microbiolspec.BAI-0015-2019
Three-Dimensional Chromatin Structure of the EBV Genome: A Crucial Factor in Viral Infection.ReviewViruses · 2023Caruso LB, Maestri D, Tempera IDOI: 10.3390/v15051088

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Wikidata facts

Image: 30nm Chromatin Structures.png

Show 2 more facts

Commons category: Chromatin
exact match: purl.obolibrary.org/obo/GO_0000785

Sources (4)

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~26 min read

Article

27 sections

Contents

Basic chromatin structure
Nucleosomes
Historical 30-nm fiber model
Three-dimensional genome organization
Chromatin loops
TADs
Chromatin compartments
Chromosome territories
Chromatin dynamics and regulation
Histone modifications
Chromatin remodeling
Transcriptional bursting
Structure of DNA
Chromatin during the cell cycle
Spatial organization of chromatin in the cell nucleus
Cell-cycle dependent structural organization
Specialized chromatin states
Sperm chromatin
Chromatin and DNA repair
Methods to study chromatin
Physical and topological properties
Chromatin knots
See also
Notes
References
Additional sources
External links

thumb|358x358px|The major structures in DNA compaction: DNA, the [[nucleosome, the 11 nm beads on a string chromatin fibre and the metaphase chromosome.]]

Chromatin is a complex of DNA and protein responsible for condensing and packaging chromosomal DNA. Chromatin is found in both bacterial and eukaryotic cells.This article deals almost exclusively with eukaryotic chromatin.