PHF1
Sign in to saveAlso known as MTF2L2, PCL1, PHF2, TDRD19C, hPHF1, PHD finger protein 1
PHD finger protein 1 is a protein that in humans is encoded by the PHF1 gene.
Gene data
PHF1- Name
- PHD finger protein 1
- Type
- protein-coding
- Position
- 33,410,360–33,416,453 (+)
- Aliases
- MTF2L2, PCL1, TDRD19C, hPHF1
- Ensembl
- ENSG00000225553
- RefSeq RNA
- NM_002636.5, NM_024165.3, NR_027692.2, XM_011514662.2, XM_011514663.2
- RefSeq protein
- NP_002627.2, NP_077084.2, XP_011512964.2, XP_011512965.2, XP_011512966.2
This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
PHD finger protein 1
- Symbol
- PHF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:33,410,360-33,416,453
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 7567
- genomic start
- 33378176
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5252
- chromosome
- human chromosome 6
- genomic end
- 33384230
- cytogenetic location
- 6p21.32
- expressed in
- gastric mucosa
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- References
- Further reading
- External links
PHD finger protein 1 is a protein that in humans is encoded by the PHF1 gene.
== Function ==
Excerpted from Wikipedia’s “PHF1” article, available under the CC BY-SA 4.0 licence.