Forkhead box E1
Sign in to saveAlso known as forkhead box protein E2, forkhead box protein E1, forkhead-related protein FKHL15, HFKL5, thyroid transcription factor 2, HFKH4, TTF-2, forkhead, drosophila, homolog-like 15
Forkhead box protein E1 is a protein that in humans is encoded by the FOXE1 gene.
Protein · UniProt
Forkhead box protein E1
- Gene
- FOXE1
- Organism
- Homo sapiens (Human)
- Length
- 373 aa
- Molecular mass
- 38,076 Da
- Evidence
- 1: Evidence at protein level
Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression
Swiss-Prot (reviewed) · via UniProt
~1 min read
Article
8 sectionsContents
- Location
- Function
- Clinical significance
- Tissue localization
- See also
- References
- Further reading
- External links
Forkhead box protein E1 is a protein that in humans is encoded by the FOXE1 gene.
== Location == The FOXE1 gene is located on the long (q) arm of chromosome 9 at position 22