Also known as AP-2rep, AP2REP, HSPC122, Kruppel-like factor 12, Kruppel like factor 12
Krueppel-like factor 12 is a protein that in humans is encoded by the KLF12 gene.
Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Biological process
~1 min read
Krueppel-like factor 12 is a protein that in humans is encoded by the KLF12 gene.
Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.
Molecular function
via MyGene.info
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).