ZBTB20

Name

zinc finger and BTB domain containing 20

Type

protein-coding

Position

114,314,500–115,147,356 (−)

Aliases

DPZF, HOF, ODA-8S, PRIMS, ZNF288

Ensembl

ENSG00000181722

RefSeq RNA

NM_001164342.2, NM_001164343.2, NM_001164344.4, NM_001164345.4, NM_001164346.2

RefSeq protein

NP_001157814.1, NP_001157815.1, NP_001157816.1, NP_001157817.1, NP_001157818.1

This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017].

via MyGene.info

Gene · Ensembl

zinc finger and BTB domain containing 20

Symbol

ZBTB20

Biotype

Protein coding

Organism

Homo sapiens

Location

3:114,314,500-115,147,356

Strand

Reverse (−)

Assembly

GRCh38