NFYB
Sign in to saveAlso known as CBF-A, CBF-B, HAP3, NF-YB, nuclear transcription factor Y subunit beta
Nuclear transcription factor Y subunit beta is a protein that in humans is encoded by the NFYB gene.
Gene data
NFYB- Name
- nuclear transcription factor Y subunit beta
- Type
- protein-coding
- Position
- 104,117,080–104,138,293 (−)
- Aliases
- CBF-A, CBF-B, HAP3, NF-YB
- Ensembl
- ENSG00000120837
- RefSeq RNA
- NM_001414518.1, NM_001414519.1, NM_001414520.1, NM_001414521.1, NM_001414522.1
- RefSeq protein
- NP_001401447.1, NP_001401448.1, NP_001401449.1, NP_001401450.1, NP_001401451.1
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
nuclear transcription factor Y subunit beta
- Symbol
- NFYB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:104,117,080-104,138,293
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
Nuclear transcription factor Y subunit beta is a protein that in humans is encoded by the NFYB gene.
== Function ==
Excerpted from Wikipedia’s “NFYB” article, available under the CC BY-SA 4.0 licence.