PITX3
Sign in to saveAlso known as ASMD, ASOD, CTPP4, CTRCT11, PTX3, paired like homeodomain 3, ASGD1
Pituitary homeobox 3 is a protein that in humans is encoded by the PITX3 gene.
Gene data
PITX3- Name
- paired like homeodomain 3
- Type
- protein-coding
- Position
- 102,229,754–102,241,512 (−)
- Aliases
- ASGD1, ASMD, ASOD, CTPP4, CTRCT11
- Ensembl
- ENSG00000107859
- RefSeq RNA
- NM_005029.4, XM_047425352.1, XM_054366090.1
- RefSeq protein
- NP_005020.1, XP_047281308.1, XP_054222065.1
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation during eye development. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis and congenital cataracts. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Wikidata facts
- Instance of
- gene
- Image
- Protein PITX3 PDB 1yz8.png
Show 5 more facts
- HomoloGene ID
- 3689
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5309
- cytogenetic location
- 10q24.32
- expressed in
- kidney
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Clinical significance
- References
- Further reading
- External links
Pituitary homeobox 3 is a protein that in humans is encoded by the PITX3 gene.
== Function ==
Excerpted from Wikipedia’s “PITX3” article, available under the CC BY-SA 4.0 licence.