CELF1
Sign in to saveAlso known as BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, NAB50, NAPOR, hNab50
CUG triplet repeat, RNA binding protein 1, also known as CUGBP1, is a protein which in humans is encoded by the CUGBP1 gene.
Gene data
CELF1- Name
- CUGBP Elav-like family member 1
- Type
- protein-coding
- Position
- 47,465,933–47,565,569 (−)
- Aliases
- BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, NAB50, NAPOR, hNab50
- Ensembl
- ENSG00000149187
- RefSeq RNA
- NM_001025596.3, NM_001172639.2, NM_001172640.2, NM_001330272.2, NM_001376369.1
- RefSeq protein
- NP_001020767.1, NP_001166110.1, NP_001166111.1, NP_001317201.1, NP_001363298.1
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
CUGBP Elav-like family member 1
- Symbol
- CELF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:47,465,933-47,565,569
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CUGBP1 PDB 2cpz.png
Show 5 more facts
- HomoloGene ID
- 136342
- genomic start
- 47487496
- exact match
- identifiers.org/ncbigene/10658
- genomic end
- 47587121
- cytogenetic location
- 11p11.2
via Wikidata · CC0
~4 min read
Article
5 sectionsContents
- Function
- mRNA degradation factor
- References
- External links
- Further reading
CUG triplet repeat, RNA binding protein 1, also known as CUGBP1, is a protein which in humans is encoded by the CUGBP1 gene.
==Function==