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GeneQ18045591· pop 6· linked from 52 articles

NCAPG

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Also known as CAPG, CHCG, NY-MEL-3, YCG1, non-SMC condensin I complex subunit G

Condensin complex subunit 3 also known as condensin subunit CAP-G (CAP-G) or non-SMC condensin I complex subunit G (NCAPG) is a protein that in humans is encoded by the NCAPG gene. CAP-G is a subunit of condensin I, a large protein complex involved in chromosome condensation.

Gene data

NCAPG
Name
non-SMC condensin I complex subunit G
Type
protein-coding
Position
17,810,844–17,848,064 (+)
Aliases
CAPG, CHCG, NY-MEL-3, YCG1
Ensembl
ENSG00000109805
RefSeq RNA
NM_022346.5, NR_073124.2, XM_017008543.3, XM_047416072.1, XM_047416073.1
RefSeq protein
NP_071741.2, XP_016864032.1, XP_047272028.1, XP_047272029.1, XP_054206685.1

This gene encodes a subunit of the condensin complex, which is responsible for the condensation and stabilization of chromosomes during mitosis and meiosis. Phosphorylation of the encoded protein activates the condensin complex. There are pseudogenes for this gene on chromosomes 8 and 15. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].

Gene Ontology

Molecular function

protein binding

Pathways

Cell CycleCell CycleCondensation of Prometaphase ChromosomesCondensation of Prometaphase ChromosomesMitotic PrometaphaseMitotic PrometaphaseM PhaseM PhaseCell Cycle, MitoticCell Cycle, Mitotic

via MyGene.info

Gene · Ensembl

non-SMC condensin I complex subunit G

Symbol
NCAPG
Biotype
Protein coding
Organism
Homo sapiens
Location
4:17,810,844-17,848,064
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
44071
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/64151
genomic end
17844865
genomic start
17810979
chromosome
human chromosome 4
cytogenetic location
4p15.31
expressed in
amniotic fluid
Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections
Contents
  • Interactions
  • References
  • Further reading

Condensin complex subunit 3 also known as condensin subunit CAP-G (CAP-G) or non-SMC condensin I complex subunit G (NCAPG) is a protein that in humans is encoded by the NCAPG gene. CAP-G is a subunit of condensin I, a large protein complex involved in chromosome condensation.

== Interactions ==

Excerpted from Wikipedia’s “NCAPG” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

via Wikidata sitelinks · CC0