Structure via PubChem · Public domain (PubChem)
chalcone
Sign in to saveAlso known as trans-chalcone, trans-benzylideneacetophenone, (E)-1,3-diphenyl-2-propen-1-one, (E)-chalcone
Chalcone is the organic compound C6H5C(O)CH=CHC6H5. It is an α,β-unsaturated ketone. A variety of important biological compounds are known collectively as chalcones or chalconoids. They are widely known bioactive substances, fluorescent materials, and chemical intermediates.
Chemical data
- Formula
- C15H12O
- Molecular weight
- 208.25 g/mol
- IUPAC name
- (E)-1,3-diphenylprop-2-en-1-one
- SMILES
- C1=CC=C(C=C1)/C=C/C(=O)C2=CC=CC=C2
- InChIKey
- DQFBYFPFKXHELB-VAWYXSNFSA-N
- XLogP
- 3.1
- Polar surface area
- 17.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Research
11,748 papers- Chalcone Derivatives: Role in Anticancer Therapy.Biomolecules · 2021
- Chalcone Derivatives as Antibacterial Agents: An Updated Overview.Current medicinal chemistry · 2024
- Significance of Chalcone Scaffolds in Medicinal Chemistry.Topics in current chemistry (Cham) · 2024
- Radiolabeled Chalcone Derivatives as Potential Radiotracers for β-Amyloid Plaques Imaging.Molecules (Basel, Switzerland) · 2023
- Pharmacotherapeutics Applications and Chemistry of Chalcone Derivatives.Molecules (Basel, Switzerland) · 2022
via PubMed
Wikidata facts
- Mass
- 208.088815004
Show 5 more facts
- Commons category
- Chalcone
- chemical formula
- C₁₅H₁₂O
- canonical SMILES
- C1=CC=C(C=C1)C=CC(=O)C2=CC=CC=C2
- melting point
- 56
- isomeric SMILES
- C1=CC=C(C=C1)/C=C/C(=O)C2=CC=CC=C2
via Wikidata · CC0
~3 min read
Article
11 sectionsContents
- Chemical properties
- Biosynthesis
- Laboratory synthesis
- Potential pharmacology
- Uses
- Medicinal uses
- Industrial uses
- Uses in organic chemistry
- See also
- References
- External links
Chalcone is the organic compound C6H5C(O)CH=CHC6H5. It is an α,β-unsaturated ketone. A variety of important biological compounds are known collectively as chalcones or chalconoids. They are widely known bioactive substances, fluorescent materials, and chemical intermediates.
== Chemical properties == Chalcones have two absorption maxima at 280 nm and 340 nm.