chitinase
Also known as 1,4-beta-poly-N-acetylglucosaminidase, poly-beta-glucosaminidase, beta-1,4-poly-N-acetyl glucosamidinase, poly[1,4-(N-acetyl-beta-D-glucosaminide)] glycanohydrolase, chitinases
Chitinases (, chitodextrinase, 1,4-β-poly-N-acetylglucosaminidase, poly-β-glucosaminidase, β-1,4-poly-N-acetyl glucosamidinase, poly[1,4-(N-acetyl-β-D-glucosaminide)] glycanohydrolase, (1→4)-2-acetamido-2-deoxy-β-D-glucan glycanohydrolase; systematic name (1→4)-2-acetamido-2-deoxy-β-D-glucan glycanohydrolase) are hydrolytic enzymes that break down glycosidic bonds in chitin. They catalyse the following reaction:
Key facts
- Protein.Name
- chitinase 1 (chitotriosidase)
- Protein.caption
- Homo sapiens chitotriosidase bound with two molecules of inhibitor allosamidin
- Protein.image
- Homo sapiens chitotriosidase 1HKK.png
- Protein.HGNCid
- 1936
- Protein.Symbol
- CHIT1
- Protein.EntrezGene
- 1118
- Protein.OMIM
- 600031
- Protein.RefSeq
- NM_003465
- Protein.UniProt
- Q13231
- Protein.Chromosome
- 1
- Protein.Arm
- q
- Protein.Band
- 31
- Protein.LocusSupplementaryData
Article
10 sectionsContents
- Species distribution
- Classification
- Function
- Clinical significance
- Regulation in fungi
- Presence in food
- Applications
- See also
- References
- External links
Chitinases (, chitodextrinase, 1,4-β-poly-N-acetylglucosaminidase, poly-β-glucosaminidase, β-1,4-poly-N-acetyl glucosamidinase, poly[1,4-(N-acetyl-β-D-glucosaminide)] glycanohydrolase, (1→4)-2-acetamido-2-deoxy-β-D-glucan glycanohydrolase; systematic name (1→4)-2-acetamido-2-deoxy-β-D-glucan glycanohydrolase) are hydrolytic enzymes that break down glycosidic bonds in chitin. They catalyse the following reaction: Random endo-hydrolysis of N-acetyl-β-D-glucosaminide (1→4)-β-linkages in chitin and chitodextrins
As chitin is a component of the cell walls of fungi and exoskeletal elements of some animals (including mollusks and arthropods), chitinases are generally found in organisms that either need to reshape their own chitin or dissolve and digest the chitin of fungi or animals.