chitinase
Sign in to saveAlso known as 1,4-beta-poly-N-acetylglucosaminidase, poly-beta-glucosaminidase, beta-1,4-poly-N-acetyl glucosamidinase, poly[1,4-(N-acetyl-beta-D-glucosaminide)] glycanohydrolase, chitinases
Chitinases (, chitodextrinase, 1,4-β-poly-N-acetylglucosaminidase, poly-β-glucosaminidase, β-1,4-poly-N-acetyl glucosamidinase, poly[1,4-(N-acetyl-β-D-glucosaminide)] glycanohydrolase, (1→4)-2-acetamido-2-deoxy-β-D-glucan glycanohydrolase; systematic name (1→4)-2-acetamido-2-deoxy-β-D-glucan glycanohydrolase) are hydrolytic enzymes that break down glycosidic bonds in chitin. They catalyse the following reaction:
Key facts
- Protein.Name
- chitinase 1 (chitotriosidase)
- Protein.caption
- Homo sapiens chitotriosidase bound with two molecules of inhibitor allosamidin
- Protein.image
- Homo sapiens chitotriosidase 1HKK.png
- Protein.HGNCid
- 1936
- Protein.Symbol
- CHIT1
- Protein.EntrezGene
- 1118
- Protein.OMIM
- 600031
- Protein.RefSeq
- NM_003465
- Protein.UniProt
- Q13231
- Protein.Chromosome
- 1
- Protein.Arm
- q
- Protein.Band
- 31
- Protein.LocusSupplementaryData
- -q32
via Wikipedia infobox
Research
10,340 papers- Chitinases and chitinase-like proteins in asthma.Seminars in immunology · 2023
- Bacterial Chitinase System as a Model of Chitin Biodegradation.Advances in experimental medicine and biology · 2019
- Chitinases and chitinase-like proteins as biomarkers in neurologic disorders.Neurology(R) neuroimmunology & neuroinflammation · 2021
- Purification and characterization of chitinase from Paenibacillus sp. .Biotechnology and applied biochemistry · 2021
- Prospects of chitinase in sustainable farming and modern biotechnology: an update on recent progress and challenges.Biotechnology & genetic engineering reviews · 2024
via PubMed
Wikidata facts
Show 3 more facts
- EC enzyme number
- 3.2.1.14
- exact match
- www.cazy.org/fam/GH19.html
- Commons category
- Chitinases
Sources (2)
via Wikidata · CC0
~10 min read
Article
10 sectionsContents
- Species distribution
- Classification
- Function
- Clinical significance
- Regulation in fungi
- Presence in food
- Applications
- See also
- References
- External links
Chitinases (, chitodextrinase, 1,4-β-poly-N-acetylglucosaminidase, poly-β-glucosaminidase, β-1,4-poly-N-acetyl glucosamidinase, poly[1,4-(N-acetyl-β-D-glucosaminide)] glycanohydrolase, (1→4)-2-acetamido-2-deoxy-β-D-glucan glycanohydrolase; systematic name (1→4)-2-acetamido-2-deoxy-β-D-glucan glycanohydrolase) are hydrolytic enzymes that break down glycosidic bonds in chitin. They catalyse the following reaction: Random endo-hydrolysis of N-acetyl-β-D-glucosaminide (1→4)-β-linkages in chitin and chitodextrins
As chitin is a component of the cell walls of fungi and exoskeletal elements of some animals (including mollusks and arthropods), chitinases are generally found in organisms that either need to reshape their own chitin or dissolve and digest the chitin of fungi or animals.