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clofoctol

Structure via PubChem · Public domain (PubChem)

EntityQ3680895· pop 8· linked from 50 articles

Clofoctol is a bacteriostatic antibiotic. It is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. It has been marketed in France till 2005 under the trade name Octofene and in Italy as Gramplus.

Chemical data

Formula
C21H26Cl2O
Molecular weight
365.3 g/mol
IUPAC name
2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol
SMILES
CC(C)(C)CC(C)(C)C1=CC(=C(C=C1)O)CC2=C(C=C(C=C2)Cl)Cl
InChIKey
HQVZOORKDNCGCK-UHFFFAOYSA-N
XLogP
8.1
Polar surface area
20.2 Ų
H-bond donors
1
H-bond acceptors
1
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule
Indications
bacterial disease

via ChEMBL · EBI

Wikidata facts

Mass
364.136
Show 2 more facts
canonical SMILES
CC(C)(C)CC(C)(C)C1=CC(=C(C=C1)O)CC2=C(C=C(C=C2)Cl)Cl
chemical formula
C₂₁H₂₆Cl₂O
Sources (4)

via Wikidata · CC0

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Encyclopedic overview

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Contents
  • References

Clofoctol is a bacteriostatic antibiotic. It is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. It has been marketed in France till 2005 under the trade name Octofene and in Italy as Gramplus.

It is only functional against Gram-positive bacteria.

Excerpted from Wikipedia’s “clofoctol” article, available under the CC BY-SA 4.0 licence.

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