Structure via PubChem · Public domain (PubChem)
coumachlor
Sign in to saveCoumachlor is a first generation anticoagulant rodenticide which blocks formation of prothrombin and inhibits blood coagulation causing death by internal haemorrhage. The chemical can be absorbed through the skin. The symptoms of human contact can be nosebleeds, bleeding gums, bloody urine, extensive bruising in the absence of injury, fatigue, shortness of breath (dyspnea) on exertion. The human consumption or inhalation of compound can also cause fluid in lungs (pulmonary edema).
In the Vinony graph
Vinony's link graph records 1 inbound reference to coumachlor, and connects out to Wayback Machine, chemical formula and fatigue.
Vinony files it under Anticoagulant rodenticides and ECHA InfoCard ID from Wikidata.
Vinony links it to 5 Wikipedia language editions.
Chemical data
- Formula
- C19H15ClO4
- Molecular weight
- 342.8 g/mol
- IUPAC name
- 3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxychromen-2-one
- SMILES
- CC(=O)CC(C1=CC=C(C=C1)Cl)C2=C(C3=CC=CC=C3OC2=O)O
- InChIKey
- DEKWZWCFHUABHE-UHFFFAOYSA-N
- XLogP
- 3.3
- Polar surface area
- 63.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
44 papers- Preparation of molecularly imprinted polymers for warfarin and coumachlor by multi-step swelling and polymerization method and their imprinting effects.Journal of chromatography. A · 2017
- Comprehensive Evaluation of an HPLC-MS-MS Method for Quantitation of Seven Anti-Coagulant Rodenticides and Dicoumarol in Animal Serum.Journal of analytical toxicology · 2023
- Acute bromadiolone intoxication.Journal of analytical toxicology · 2006
- Studies on chemical determination of warfar in and coumachlor and their toxicity for dog and swine.Acta pharmacologica et toxicologica · 1959
- Comparison of the anticoagulant action of 3-(alpha-p-chlorphenyl-beta-acetylethyl)-4-hydroxycoumarin (coumachlor) and dicoumarol in chicks and rats.Acta pharmacologica et toxicologica · 1953
via PubMed
Wikidata facts
- Instance of
- rodenticide
- Subclass of
- chemical compound
- Mass
- 342.066
- Has use
- rodenticide
Show 3 more facts
- chemical formula
- C₁₉H₁₅ClO₄
- canonical SMILES
- CC(=O)CC(C1=CC=C(C=C1)Cl)C2=C(C3=CC=CC=C3OC2=O)O
- subject has role
- anticoagulant
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Coumachlor is a first generation anticoagulant rodenticide which blocks formation of prothrombin and inhibits blood coagulation causing death by internal haemorrhage. The chemical can be absorbed through the skin. The symptoms of human contact can be nosebleeds, bleeding gums, bloody urine, extensive bruising in the absence of injury, fatigue, shortness of breath (dyspnea) on exertion. The human consumption or inhalation of compound can also cause fluid in lungs (pulmonary edema).
==References==
Excerpted from Wikipedia’s “coumachlor” article, available under the CC BY-SA 4.0 licence.