CPA1
Sign in to saveAlso known as CPA, carboxypeptidase A1
protein-coding gene in the species Homo sapiens
Gene data
CPA1- Name
- carboxypeptidase A1
- Type
- protein-coding
- Position
- 130,380,339–130,388,114 (+)
- Aliases
- CPA
- Ensembl
- ENSG00000091704
- RefSeq RNA
- NM_001868.4
- RefSeq protein
- NP_001859.1
This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [provided by RefSeq, Jan 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
carboxypeptidase A1
- Symbol
- CPA1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:130,380,339-130,388,114
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CPA1 PDB 2V77.png
Show 7 more facts
- HomoloGene ID
- 55609
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1357
- chromosome
- human chromosome 7
- genomic start
- 130020180
- genomic end
- 130027955
- cytogenetic location
- 7q32.2
Sources (4)
via Wikidata · CC0