CRHBP

Also known as CRF-BP, CRFBP, corticotropin releasing hormone binding protein

Corticotropin-releasing factor-binding protein is a protein that in humans is encoded by the CRHBP gene. It belongs to corticotropin-releasing hormone binding protein family.

Gene data

CRHBP

Name: corticotropin releasing hormone binding protein
Type: protein-coding
Position: 76,952,857–76,981,315 (+)
Aliases: CRF-BP, CRFBP
Ensembl: ENSG00000145708
RefSeq RNA: NM_001882.4, XM_047416736.1, XR_008487082.1, XR_948235.4
RefSeq protein: NP_001873.2, XP_047272692.1

Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. [provided by RefSeq, Jul 2008].

Pathways

Signal Transduction Signaling by GPCR Class B/2 (Secretin family receptors)GPCR ligand binding Corticotropin-releasing hormone signaling pathway

via MyGene.info

Gene · Ensembl

corticotropin releasing hormone binding protein

Symbol: CRHBP
Biotype: Protein coding
Organism: Homo sapiens
Location: 5:76,952,857-76,981,315
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

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Encyclopedic overview

3 sections

Contents

References
External links
Further reading

Corticotropin-releasing factor-binding protein is a protein that in humans is encoded by the CRHBP gene. It belongs to corticotropin-releasing hormone binding protein family.

Excerpted from Wikipedia’s “CRHBP” article, available under the CC BY-SA 4.0 licence.