CSN2
Sign in to saveAlso known as CASB, casein beta, PDC213
Beta-casein is a protein that in humans is encoded by the CSN2 gene. It is in the class of phosphoproteins and generally occurs in mammalian milk.
In the Vinony graph
Vinony's link graph records 5 inbound references to CSN2, and connects out to PubMed, human chromosome 4 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 4.
Vinony links it to 7 Wikipedia language editions.
Gene data
CSN2- Name
- casein beta
- Type
- protein-coding
- Position
- 69,955,256–69,965,728 (−)
- Aliases
- CASB, PDC213
- Ensembl
- ENSG00000135222
- RefSeq RNA
- NM_001302770.2, NM_001385731.1, NM_001891.4, XR_001756926.1, XR_001756927.1
- RefSeq protein
- NP_001289699.1, NP_001372660.1, NP_001882.1
This gene is a member of the beta casein family. There are two types of casein protein, beta (encoded by this gene) and kappa, both of which are secreted in human milk. Beta casein is the principal protein in human milk and the primary source of essential amino acids for a suckling infant. Beta and kappa casein proteins acting together form spherical micelles which bind within them important dietary minerals, such as calcium and phosphorous. In addition, the C-terminal 14 aa of the protein has antimicrobial activity, especially in preterm milk, displaying antibacterial activity against S. aureus and Y. enterocolitica. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2020].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
casein beta
- Symbol
- CSN2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:69,955,256-69,965,728
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 1426
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1447
- chromosome
- human chromosome 4
- genomic start
- 70820974
- genomic end
- 69965728
- cytogenetic location
- 4q13.3
- expressed in
- skeletal muscle
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Beta-casein is a protein that in humans is encoded by the CSN2 gene. It is in the class of phosphoproteins and generally occurs in mammalian milk.
==References==
Excerpted from Wikipedia’s “CSN2” article, available under the CC BY-SA 4.0 licence.