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cyanopindolol

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cyanopindolol

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Cyanopindolol is a drug related to pindolol which acts as both a β1 adrenoceptor antagonist and a 5-HT1A receptor antagonist. Its radiolabelled derivative iodocyanopindolol has been widely used in mapping the distribution of beta adrenoreceptors in the body.

Chemical data

Formula
C16H21N3O2
Molecular weight
287.36 g/mol
IUPAC name
4-[3-(tert-butylamino)-2-hydroxypropoxy]-1H-indole-2-carbonitrile
SMILES
CC(C)(C)NCC(COC1=CC=CC2=C1C=C(N2)C#N)O
InChIKey
QXIUMMLTJVHILT-UHFFFAOYSA-N
XLogP
2
Polar surface area
81.1 Ų
H-bond donors
3
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of
alcohols
Has part
carbon
Mass
287.163377
Show 4 more facts
chemical formula
C₁₆H₂₁N₃O₂
canonical SMILES
CC(C)(C)NCC(COC1=CC=CC2=C1C=C(N2)C#N)O
Commons category
Cyanopindolol
subject has role
beta blocker
Sources (2)

via Wikidata · CC0

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Encyclopedic overview

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Contents
  • References

Cyanopindolol is a drug related to pindolol which acts as both a β1 adrenoceptor antagonist and a 5-HT1A receptor antagonist. Its radiolabelled derivative iodocyanopindolol has been widely used in mapping the distribution of beta adrenoreceptors in the body.

== References ==

Excerpted from Wikipedia’s “cyanopindolol” article, available under the CC BY-SA 4.0 licence.

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