cyproterone acetate

Chemical data

Formula

C24H29ClO4

Molecular weight

416.9 g/mol

IUPAC name

[(1S,2S,3S,5R,11R,12S,15R,16S)-15-acetyl-9-chloro-2,16-dimethyl-6-oxo-15-pentacyclo[9.7.0.02,8.03,5.012,16]octadeca-7,9-dienyl] acetate

SMILES

CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C=C(C4=CC(=O)[C@@H]5C[C@@H]5[C@]34C)Cl)C)OC(=O)C

InChIKey

UWFYSQMTEOIJJG-FDTZYFLXSA-N

XLogP

3.6

Polar surface area

60.4 Ų

H-bond donors

0

H-bond acceptors

4

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 3

Molecule type

Small molecule

Indications

polycystic ovary syndrome, prostate adenocarcinoma, endometriosis, acne

via ChEMBL · EBI

• Cyproterone acetate for hirsutism.The Cochrane database of systematic reviews · 2003
• [Should cyproterone acetate be removed from our prescriptions?].Gynecologie, obstetrique, fertilite & senologie · 2019
• Is cyproterone acetate causing intracranial meningiomas?JPMA. The Journal of the Pakistan Medical Association · 2022
• Cyproterone acetate: a genotoxic carcinogen?Pharmacology & toxicology · 2001
• Cyproterone acetate: is it hepato- or genotoxic?Drug safety · 1996

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

416.175

Has use

medication

via Wikidata · CC0